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Registros recuperados: 124 | |
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Saut,João Paulo Elsen; Oliveira,Patrícia Magalhães de; Nasciutti,Nayara Resende; Medeiros,Alessandra Aparecida; Magalhães,Geórgia Modé; Tsuruta,Suzana Akemi; Hanna,Paul; Headley,Selwyn Arlington. |
The clinical, pathological, and immunohistochemical findings associated with a vaginal leiomyosarcoma in a 12-year-old, Senepol breed of cow from Uberlândia, Minas Gerais are described. The animal had a large ulcerative neoplastic growth that originated between the base and the left-lateral vaginal wall. Histopathology revealed a tumor formed by muscle-like cells that demonstrated cellular pleomorphism, anisokaryosis, prominent and multiple nucleoli, with rare tumor giant cells. The neoplastic growth invaded adjacent adipose tissue, and contained areas of hemorrhage with discrete accumulations of inflammatory cells. By immunohistochemistry, most neoplastic cells expressed actin, while immunoreactivity to desmin was weakly expressed. These findings support... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Bovine diseases; Immunohistochemistry; Reproductive pathology; Smooth muscle tumor. |
Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782013000500024 |
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Parra,E.R.; Falzoni,R.; Capelozzi,V.L.. |
In this study, we demonstrated the importance of telomerase protein expression and determined the relationships among telomerase, endothelin-1 (ET-1) and myofibroblasts during early and late remodeling of parenchymal and vascular areas in usual interstitial pneumonia (UIP) using 27 surgical lung biopsies from patients with idiopathic pulmonary fibrosis (IPF). Telomerase+, myofibroblasts α-SMA+, smooth muscle cells caldesmon+, endothelium ET-1+ cellularity, and fibrosis severity were evaluated in 30 fields covering normal lung parenchyma, minimal fibrosis (fibroblastic foci), severe (mural) fibrosis, and vascular areas of UIP by the point-counting technique and a semiquantitative score. The impact of these markers was determined in pulmonary functional... |
Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Idiopathic pulmonary fibrosis; Vascular activity; Immunohistochemistry; Survival. |
Ano: 2012 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000700015 |
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Oliveira Filho,R.S.; Ferreira,L.M.; Biasi,L.J.; Enokihara,M.M.S.S.; Paiva,G.R.; Wagner,J.. |
Sentinel node (SN) status is the most important prognostic factor for localized melanoma. Usually, patients with Breslow thickness of less than 1.0 mm are not included in SN protocols. However, the literature presents a rate ranging from 3 to 7% of nodal recurrence in thin melanoma. Ulceration, regression and high mitotic rate have been considered to be indications for an SN biopsy. The metastatic potential of the vertical growth phase is uncertain. To correlate pathological features in thin melanoma with SN metastasis, we reviewed 358 patients submitted to SN biopsy. Seventy-seven patients with lesions of 1 mm or smaller were included in the study group. Histological evaluation of the primary tumor included thickness, Clark level, mitotic rate,... |
Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Thin melanoma; Sentinel node; Lymphoscintigraphy; Immunohistochemistry; Micrometastasis. |
Ano: 2003 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2003000300009 |
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Registros recuperados: 124 | |
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